翻訳と辞書 Words near each other ・ Fusible link ・ Fusible plug ・ Fusicladium pisicola ・ Fusicocca-2,10(14)-diene synthase ・ Fusicoccin ・ Fusicoccum ・ Fusicoccum aesculi ・ Fusicoccum amygdali ・ Fusicoccum quercus ・ Fusicoccum ramosum ・ Fusicolla ・ Fusiconus ・ Fusicornis ・ Fusidaphne ・ Fusidaphne bullata ・ Fusidic acid ・ Fusidium ・ Fusifilum ・ Fusiform ・ Fusiform elimia ・ Fusiform face area ・ Fusiform gyrus ・ Fusignano ・ Fusigobius ・ Fusigobius aureus ・ Fusigobius pallidus ・ Fusigobius signipinnis ・ Fusil ・ Fusil Automatique Modèle 1917 ・ Fusil automático Bogotá Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Fusidic acid ： ウィキペディア英語版 Fusidic acid Fusidic acid is a bacteriostatic antibiotic that is often used topically in creams and eyedrops, but may also be given systemically as tablets or injections. The global problem of advancing antimicrobial resistance has led to a renewed interest in its use recently.〔Falagas ME, Grammatikos AP, Michalopoulos A. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther. 2008; 6(5):593-600 PMID 18847400〕 ==Pharmacology== Fusidic acid acts as a bacterial protein synthesis inhibitor by preventing the turnover of elongation factor G (EF-G) from the ribosome. Fusidic acid is effective primarily on gram-positive bacteria such as ''Staphylococcus'' species, ''Streptococcus'' species,〔Leclercq R, Bismuth, R, Casin, I, Cavallo, JD, Croize, J, Felten, A, Goldstein, F, Monteil, H, Quentin-Noury, C, Reverdy, M, Vergnaud, M, Roiron, R. (2000) In Vitro Activity of Fusidic Acid Against Streptococci isolated form Skin and Soft Tissue Infections. ''J. Antimicrob. Chemother''. 45(1): 27-29.〕 and ''Corynebacterium'' species. Fusidic acid inhibits bacterial replication and does not kill the bacteria, and is therefore termed "bacteriostatic". Fusidic acid is a true antibiotic, derived from the fungus ''Fusidium coccineum'' and was developed by Leo Pharma in Ballerup, Denmark and released for clinical use in the 1960s. It has also been isolated from ''Mucor ramannianus'' and ''Isaria kogana''. The drug is licensed for use as its sodium salt sodium fusidate, and it is approved for use under prescription in South Korea, Japan, UK, Canada, Europe, Australia, New Zealand, Thailand, India and Taiwan. A different oral dosing regimen, based on the compound's pharmacokinetic/pharmacodynamic (PK-PD) profile is in clinical development in the U.S.〔Moriarty SR, Clark K, Scott D, Degenhardt TP, Fernandes P, Craft JC, Corey GR, Still JG and Das A (2010). 50th Interscience Conference on Antimicrobial Agents and Chemotherapy, Abstract L1-1762〕 as Taksta. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Fusidic acid」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.